5-Chlorophthalazine CAS 78032-08-3
| CAS No. | 78032-08-3 |
| Molecular Formula | C8H5ClN2 |
| Molecular Weight | 164.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chlorophthalazine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chlorophthalazine (CAS 78032-08-3), molecular formula C8H5ClN2 and molecular weight 164.59 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chlorophthalazine (C8H5ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chlorophthalazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2 |
| Molecular Weight | 164.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophthalazine Standards
- 6-Chlorophthalazine (CAS 78032-07-2)
- 1-Chlorophthalazine (CAS 5784-45-2)
- 4-Chlorophthalazine-1-carbonitrile (CAS 124433-95-0)
- 1-Chlorophthalazine-6-carbaldehyde (CAS 1187244-53-6)
- 1-Chlorophthalazine-6-carboxylic acid (CAS 1416713-30-8)
- 4-Chlorophthalazine-6-carboxylic acid (CAS 2168331-87-9)
- Methyl 1-chlorophthalazine-6-carboxylate (CAS 1416713-78-4)
- Methyl 4-chlorophthalazine-6-carboxylate (CAS 1446407-53-9)
Recommended Standards
- 5-Chloro-1,7-naphthyridine (CAS 67967-10-6)
- 5-chloropyrimidine-2-carboxylic acid (CAS 38275-61-5)
- 5-Chloro[1,6]naphthyridine (CAS 23616-32-2)
- 5-Chloroquinazoline (CAS 7556-90-3)
- 5,6-Dichloro-1H,2H,3H-imidazo[4,5-b]pyridin-2-one (CAS 361365-08-4)
- 6-(Chloromethyl)benzo[de]isochromen-1(3H)-one (CAS 1018-47-9)
- 1-Ethyl-1H-benzo[d]imidazole-4,7-diol (CAS 705927-83-9)
- (Tert-butoxycarbonyl)-L-phenylalanyl-L-leucine (CAS 33014-68-5)
- Kaurenoic acid (CAS 6730-83-2)
- (4R)-4-[(3-Chloro-7-methoxy-2-quinoxalinyl)oxy]-L-proline methyl ester mesylate (CAS 1425038-20-5)
- 4-Methoxyphenyl (E)-3-(dimethylamino)acrylate (CAS 338404-00-5)
- (2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-(2-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 24624-80-4)
- 1-(5-Acetylthiophen-2-yl)-2-chloroethan-1-one (CAS 50460-05-4)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com