2,4-Dichloro-5-methylquinazoline CAS 78052-20-7
| CAS No. | 78052-20-7 |
| Molecular Formula | C9H6Cl2N2 |
| Molecular Weight | 213.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2,4-Dichloro-5-methylquinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2,4-Dichloro-5-methylquinazoline (CAS 78052-20-7), a certified reference material (molecular formula C9H6Cl2N2, MW 213.06 g/mol) for analytical method development and quality control.
Structurally, 2,4-Dichloro-5-methylquinazoline (C9H6Cl2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 213.06 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H6Cl2N2 |
| Molecular Weight | 213.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 6,7-Dichloro-2-methylquinoxaline (CAS 108653-55-0)
- methyl 3,5-dichloro-1-methyl-1H-pyrazole-4-carboxylate (CAS 109056-69-1)
- 2,5-Dichloro-6-cyclopropylnicotinonitrile (CAS 1135283-17-8)
- 5,7-Dichloro-2-methyl-1,6-naphthyridine (CAS 1159811-67-2)
- 2,7-Dichloro-6-methylquinoxaline (CAS 1163123-60-1)
- 4,7-Dichloro-6-methylquinazoline (CAS 1187616-00-7)
- 2,6-Dichloro-4-methylquinazoline (CAS 1260798-81-9)
- 3,6-Dichloro-1H-indene-2-carbaldehyde (CAS 1314802-47-5)
Recommended Standards
- 2,3-Dichloro-5-methylquinoxaline (CAS 82463-30-7)
- 2,4-Dichloro-6-methyl-1,5-naphthyridine (CAS 959007-01-3)
- 2-(3,4-Dichlorophenyl)imidazole (CAS 4308-27-4)
- 2,4-dichloro-6-methylquinazoline (CAS 39576-82-4)
- Urolithin E (CAS 1453297-45-4)
- 4-Methyl-5-(5-methylthien-3-yl)-4H-1,2,4-triazole-3-thiol (CAS 588685-90-9)
- N-Methyl-2-(7-oxo-3-(m-tolyl)-3,7-dihydro-6H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl)acetamide (CAS 893932-71-3)
- 1-(2-((4-Bromophenyl)thio)-4-methylquinolin-3-yl)ethan-1-one (CAS 400074-45-5)
- 4-[3-(Trifluoromethyl)phenyl]-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1137666-52-4)
- 2,6-Difluoro-3-hydroxyphenylboronic Acid (CAS 957065-86-0)
- 4-(Dimethylcarbamoyl)benzene-1-sulfonyl chloride (CAS 190711-50-3)
- Biotinyl-α-CGRP (human) trifluoroacetate salt (CAS 1816258-60-2)
- 2-(2-Fluoro-5-methylphenoxy)ethane-1-sulfonyl chloride (CAS 1481672-20-1)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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