Tandospirone Impurity 6 CAS 780705-64-8
| CAS No. | 780705-64-8 |
| Molecular Formula | C13H20N4O2 |
| Molecular Weight | 264.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Tandospirone Impurity 6 (CAS 780705-64-8) is a certified pharmaceutical impurity reference standard with the molecular formula C13H20N4O2 and a molecular weight of 264.32 g/mol.
The molecular framework of Tandospirone Impurity 6 (C13H20N4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H20N4O2 |
| Molecular Weight | 264.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 4 |
Related Tandospirone Standards
- Tandospirone impurity 19 (CAS 99095-09-7)
- Tandospirone Impurity 11 (CAS 105981-33-7)
- Tandospirone Impurity 58(Lurasidone Impurity) (CAS 27862-85-7)
- Tandospirone Impurity 10 (CAS 826-62-0)
- Tandospirone Impurity 4 (CAS CATO-C4X-18754)
- Tandospirone (CAS 87760-53-0)
- Tandospirone Impurity 2 (CAS CATO-C4X-18752)
- Tandospirone Impurity 7 (CAS CATO-C4X-18757)
Recommended Standards
- Lacosamide Impurity 9 (CAS 1318777-56-8)
- Dyclonine Impurity 27 (CAS 2835362-80-4)
- Lacosamide EP Impurity C (CAS CATO-C4X-183049)
- Dyclonine Impurity 4 (CAS CATO-C4X-18814)
- Vazegepant Impurity N53 (CAS 36882-07-2)
- Entacapone Impurity 28 (CAS 2450-26-2)
- Olopatadine Impurity 25 (CAS 18355-96-9)
- 1-Cyclobutyl-1H-pyrazole-4-boronic Acid Pinacol Ester (CAS 1002309-48-9)
- 1-((Imidazo[2,1-b]thiazol-6-ylmethyl)(methyl)amino)-2-methylpropan-2-ol (CAS 1355843-65-0)
- 2-(Chloromethyl)-6-(difluoromethyl)-4-hydroxypyridine-3-carboxaldehyde (CAS 1805618-71-6)
- Diamido-dPEG<SUP>®</SUP><SUB>11</SUB>-diamine (CAS 1224728-09-9)
- Nicardipine Hydrochloride EP Impurity C (CAS 21881-77-6)
- Methyl 2-(((5-methyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)methylene)amino)acetate (CAS 338975-51-2)
- Peptide Impurity (CAS CATO-CPTD788810)
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