Methyl 4-Bromothiophene-3-carboxylate CAS 78071-37-1

Purity 97%+In StockPharmaceutical Standards
CAS No.78071-37-1
Molecular FormulaC6H5BrO2S
Molecular Weight221.07 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 4-Bromothiophene-3-carboxylate CAS 78071-37-1 chemical structure

Description

The occurrence of Methyl 4-Bromothiophene-3-carboxylate is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Methyl 4-Bromothiophene-3-carboxylate (CAS 78071-37-1) is a high-purity analytical reference standard with the molecular formula C6H5BrO2S and a molecular weight of 221.07 g/mol.

The molecular framework of Methyl 4-Bromothiophene-3-carboxylate (C6H5BrO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Methyl 4-Bromothiophene-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H5BrO2S
Molecular Weight221.07 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Halogen ContentBr-containing
Sulfur Atoms1

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