1-(4-Chlorophenyl)-2,2,3,3,3-pentafluoropropan-1-one CAS 781-97-5
| CAS No. | 781-97-5 |
| Molecular Formula | C9H4ClF5O |
| Molecular Weight | 258.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(4-Chlorophenyl)-2,2,3,3,3-pentafluoropropan-1-one (CAS 781-97-5) is a high-purity analytical reference standard with the molecular formula C9H4ClF5O and a molecular weight of 258.57 g/mol.
1-(4-Chlorophenyl)-2,2,3,3,3-pentafluoropropan-1-one (C9H4ClF5O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(4-Chlorophenyl)-2,2,3,3,3-pentafluoropropan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H4ClF5O |
| Molecular Weight | 258.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Chlorophenyl Standards
- 1-(3-Chlorophenyl)-2,2,3,3,3-pentafluoropropan-1-one (CAS 1352214-32-4)
- 6-(4-Chlorophenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione (CAS 37458-38-1)
- 7-(4-Chlorophenyl)pteridin-4(3H)-one (CAS 73318-79-3)
- 2-((4-chlorophenyl)ethynyl)-5-fluorobenzaldehyde (CAS 1939148-83-0)
- (2Z)-2-(4-chlorophenyl)-3-phenylacrylic acid (CAS 10465-70-0)
- 5-[(2-chlorophenyl)carbonyl]-2,3-dihydro-1-benzofuran (CAS 1096942-27-6)
- 2-(4-Chlorophenyl)-2,3-dihydroquinazolin-4(1h)-one (CAS 13165-11-2)
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Recommended Standards
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