(E)-4-(2,4-Dimethoxyphenyl)-4-oxo-2-butenoic acid CAS 78149-70-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-4-(2,4-Dimethoxyphenyl)-4-oxo-2-butenoic acid.

(E)-4-(2,4-Dimethoxyphenyl)-4-oxo-2-butenoic acid (CAS 78149-70-9), molecular formula C12H12O5 and molecular weight 236.22 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, (E)-4-(2,4-Dimethoxyphenyl)-4-oxo-2-butenoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (E)-4-(2,4-Dimethoxyphenyl)-4-oxo-2-butenoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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