1,3-dihydrospiro[indene-2,2’-pyrrolidine] CAS 781559-69-1
| CAS No. | 781559-69-1 |
| Molecular Formula | C12H15N |
| Molecular Weight | 173.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1,3-dihydrospiro[indene-2,2’-pyrrolidine] (CAS 781559-69-1), molecular formula C12H15N and molecular weight 173.25 g/mol, is a CATO reference standard with documented purity and traceability.
1,3-dihydrospiro[indene-2,2’-pyrrolidine] (C12H15N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15N |
| Molecular Weight | 173.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Related dihydrospiro Standards
- (2',3'-Dihydrospiro[cyclopropane-1,1'-inden]-2-yl)methanamine (CAS 1340377-50-5)
- (1',3'-Dihydrospiro[cyclopropane-1,2'-inden]-2-yl)methanamine (CAS 1484634-62-9)
- 2,3-Dihydrospiro[indene-1,3'-pyrrolidine] (CAS 16976-98-0)
- 1',3'-Dihydrospiro[cyclopentane-1,2'-indole] (CAS 7075-78-7)
- 2,3-Dihydrospiro[cyclopropane-1,4(1H)-isoquinolin]-1-one (CAS 1782267-00-8)
- (1',3'-Dihydrospiro[cyclopropane-1,2'-inden]-2-yl)methanol (CAS 331992-90-6)
- 5,6-Dihydrospiro[cyclopenta[c]pyridine-7,2'-pyrrolidine] (CAS 463303-91-5)
- 1,3-Dihydrospiro[indene-2,3'-oxetan]-5-amine (CAS 2304496-01-1)
Recommended Standards
- 1-Amino-3-(cyclohexyloxy)propan-2-ol (CAS 89100-83-4)
- 1,3,3-Trimethyl-3,4-dihydroisoquinoline (CAS 79023-51-1)
- 1-Benzyl-1,2,3,6-tetrahydropyridine (CAS 40240-12-8)
- 1',2',3',4'-Tetrahydro-[1,1'-biphenyl]-2-amine (CAS 59816-86-3)
- Methyl 3-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-3-oxopropanoate (CAS 1229625-50-6)
- 3-(2-Allylphenoxy)pyrrolidine hydrochloride (CAS 1185298-58-1)
- 2-(1,3,2-Benzodioxaphosphol-2-yl)-1,1-diphenylhydrazine (CAS 88117-08-2)
- ((2R,3R,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate (CAS 143028-98-2)
- Tert-butyl 6-(hydroxymethyl)-8-oxo-2,7-diazaspiro[4.4]Nonane-2-carboxylate (CAS 1422344-27-1)
- N-[3-(4-Amino-2-methylphenoxy)propyl]-N,N-dimethylamine (CAS 946663-43-0)
- Amorofen lmpurity 28 (CAS CATO-C4X-154228)
- (E)-[(3-Chloro-1-benzothiophen-2-yl)methylidene][(4-methylphenyl)methoxy]amine (CAS 477859-26-0)
- 4-(4,5-Dimethoxy-2-nitrophenyl)morpholine (CAS 30058-27-6)
- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
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