Methyl 2,6-dimethyl-1-oxaspiro[2.5]octane-2-carboxylate CAS 78258-29-4
| CAS No. | 78258-29-4 |
| Molecular Formula | C11H18O3 |
| Molecular Weight | 198.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 2,6-dimethyl-1-oxaspiro[2.5]octane-2-carboxylate (CAS 78258-29-4) is a high-purity analytical reference standard with the molecular formula C11H18O3 and a molecular weight of 198.26 g/mol.
The molecular framework of Methyl 2,6-dimethyl-1-oxaspiro[2.5]octane-2-carboxylate (C11H18O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2,6-dimethyl-1-oxaspiro[2.5]octane-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H18O3 |
| Molecular Weight | 198.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
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- (3R,4R)-1-Boc-pyrrolidine-3,4-dicarboxylic Acid (CAS 1807916-65-9)
- 3-(2-Fluoro-phenoxy)-azetidine hydrochloride (CAS 1401786-30-8)
- 2-(Aminomethyl)-6-cyano-3-(difluoromethyl)pyridine-4-carboxylic acid (CAS 1806010-87-6)
- Ethyl 1-(methylamino)cyclopentane-1-carboxylate (CAS 90950-20-2)
- 2,5-Dimethyl-N,N-diphenylbenzenesulfonamide (CAS 67811-09-0)
- 1-(5-Chloro-2-methoxybenzyl)cyclopropane-1-carboxylic acid (CAS 1268147-95-0)
- Semaglutide impurity 210 (CAS CATO-C4X-2226210)
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