3-Trifluoromethylmethacrylanilide CAS 783-05-1
| CAS No. | 783-05-1 |
| Molecular Formula | C11H10F3NO |
| Molecular Weight | 229.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Trifluoromethylmethacrylanilide.
3-Trifluoromethylmethacrylanilide (CAS 783-05-1) is a high-purity analytical reference standard with the molecular formula C11H10F3NO and a molecular weight of 229.20 g/mol.
The molecular framework of 3-Trifluoromethylmethacrylanilide (C11H10F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Trifluoromethylmethacrylanilide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10F3NO |
| Molecular Weight | 229.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 3,3,3-Trifluoro-2-(1h-pyrrolo[2,3-b]pyridin-3-yl)propan-1-amine (CAS 953899-12-2)
- 4-(2-Amino-4-(trifluoromethyl)phenyl)but-3-yn-1-ol (CAS 2589160-55-2)
- 3-(3-(Trifluoromethyl)-5,6-dihydrocyclopenta[c]pyrazol-2(4h)-yl)propanenitrile (CAS 938018-22-5)
- 4-(5-(Pyridin-3-yl)-1H-1,2,3-triazol-1-yl)-1,2,5-oxadiazol-3-amine (CAS 890093-97-7)
- N-(2-Fluoro-4-(methylsulfonyl)phenyl)-6-(4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-5-nitropyrimidin-4-amine (CAS 733750-99-7)
- (2-(2-Methylpyridin-3-yl)pyrrolidin-1-yl)(phenyl)methanone (CAS 1352485-02-9)
- (Phenylthio)(triphenylphosphoranylidene)methyl acetate (CAS 442691-87-4)
- 3-((3-Chlorophenoxy)methyl)azetidine (CAS 1332301-04-8)
- 6,7-Dimethoxyisoquinoline-4-carbonitrile (CAS 18029-62-4)
- 1h-Imidazole-2-carbohydrazide (CAS 68251-67-2)
- 1-(2-Chloro-6-methylpyridin-4-yl)ethanone (CAS 890406-52-7)
- (E)-4-fluorostyrylboronic acid 214907-24-1 A22922 trans-2-(4-Fluorophenyl)vinylboronic acid (CAS 214907-24-1)
- (2-Chloro-acetyl)-urea (CAS 4791-21-3)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
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