6-Bromo-2,3-dihydro-1H-indene-1-carbonitrile CAS 783335-58-0
| CAS No. | 783335-58-0 |
| Molecular Formula | C10H8BrN |
| Molecular Weight | 222.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Bromo-2,3-dihydro-1H-indene-1-carbonitrile (CAS 783335-58-0), molecular formula C10H8BrN and molecular weight 222.08 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Bromo-2,3-dihydro-1H-indene-1-carbonitrile (C10H8BrN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8BrN |
| Molecular Weight | 222.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2,3-dihydro-1H-indene-1-carbonitrile (CAS 1033811-54-9)
- 3-Bromo-1-methylisoquinoline (CAS 1041263-08-4)
- 4-Bromo-1-methylisoquinoline (CAS 104704-40-7)
- 4-Bromo-6-methylquinoline (CAS 1070879-23-0)
- 4-Bromo-7-methyl-quinoline (CAS 1070879-24-1)
- 5-Bromo-3-methoxypicolinaldehyde (CAS 1087659-24-2)
- 5-Bromo-7-methylquinoline (CAS 1126824-42-7)
- 5-Bromo-6-methylisoquinoline (CAS 1146298-61-4)
Recommended Standards
- 6-(Bromomethyl)isoquinoline (CAS 752183-00-9)
- 6-Bromo-3-methylquinoline (CAS 97041-63-9)
- 5-Bromo-8-methylquinoline (CAS 74316-55-5)
- 6-Bromo-4-methylisoquinoline (CAS 958880-28-9)
- (1-(4-Chlorobenzyl)piperidin-4-yl)methanamine (CAS 226249-40-7)
- 6-Fluoro-3,4-dihydro-2H-pyrano[2,3-b]pyridine (CAS 1228666-24-7)
- 2-Bromo-N-(2-methyl-4-nitrophenyl)acetamide (CAS 57339-08-9)
- Cyclopentyl(2-((3-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone (CAS 851805-56-6)
- 2-(Acetamido(thiophen-2-yl)methyl)malonic acid (CAS 874533-60-5)
- Sodium (E)-1-Cyano-3-ethoxy-3-oxo-1-propen-2-olate (CAS 627076-29-3)
- 13-O-Deacetyltaxumairol Z (CAS 220935-39-7)
- 5-Bromoimidazo[1,2-a]pyrimidine (CAS 1784394-19-9)
- 4-Methylisothiazole-5-carboxylic acid (CAS 15901-61-8)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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