5-Iodo-2-(methylthio)thiophene-3-carboxylic acid CAS 78395-05-8
| CAS No. | 78395-05-8 |
| Molecular Formula | C6H5IO2S2 |
| Molecular Weight | 300.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Iodo-2-(methylthio)thiophene-3-carboxylic acid (CAS 78395-05-8) is a high-purity analytical reference standard with the molecular formula C6H5IO2S2 and a molecular weight of 300.14 g/mol.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system, 5-Iodo-2-(methylthio)thiophene-3-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 300.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-Iodo-2-(methylthio)thiophene-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5IO2S2 |
| Molecular Weight | 300.14 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | I-containing |
| Sulfur Atoms | 2 |
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Recommended Standards
- 4-Chloro-N-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)butanamide (CAS 89757-65-3)
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- 4-Chloro-N-(5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl)butanamide (CAS 90147-10-7)
- Ethyl 1-(3,5-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxylate (CAS 338408-01-8)
- 4-fluoro-5,6-dimethoxy-benzothiophene (CAS 1934872-99-7)
- 4,4',4'',4'''-(21H,23H-Porphine-5,10,15,20-tetrayl)tetrakis[benzaldehyde] (CAS 150805-46-2)
- 5-(1,2,3-Thiadiazol-4-yl)thiophene-2-sulfonyl chloride (CAS 320421-81-6)
- N-(3,4-Dimethoxyphenyl)-3-nitro-4-(1H-1,2,4-triazol-1-yl)benzamide (CAS 338407-92-4)
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- Clindamycin Impurity 167 (CAS CATO-C4X-1341167)
- Semaglutide impurity 61 (CAS CATO-C4X-222661)
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