2-(3,5-dioxo-1,2,4-triazolidin-4-yl)acetic acid CAS 78409-55-9
| CAS No. | 78409-55-9 |
| Molecular Formula | C4H5N3O4 |
| Molecular Weight | 159.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(3,5-dioxo-1,2,4-triazolidin-4-yl)acetic acid (CAS 78409-55-9), a certified reference material (molecular formula C4H5N3O4, MW 159.10 g/mol) for analytical method development and quality control.
2-(3,5-dioxo-1,2,4-triazolidin-4-yl)acetic acid (C4H5N3O4) contains a carbohydrate-derived structure, an amide group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H5N3O4 |
| Molecular Weight | 159.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 3 |
Related dioxo Standards
- 4,6-Dioxo-1,3,5-triazinane-2-carboxamide (CAS 89281-55-0)
- 5,6-dioxo-1,4-dihydropyrazine-2-carboxylic acid (CAS 77168-80-0)
- 285978-19-0 N-[2,5-Dioxo(4-~13~C,3-~15~N)imidazolidin-4-yl]urea DTXSID20745769 (CAS 285978-19-0)
- 2,2-dioxo-2λ⁶-thiaspiro[3.3]heptan-6-one (CAS 1936319-38-8)
- (2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)boronic acid (CAS 70523-22-7)
- 2-(2,5-Dioxo-3-pyrrolidinyl)acetic Acid (CAS 84767-78-2)
- 2,6-Dioxo-4-piperidinecarboxylic Acid (CAS 6973-55-3)
- Methyl 2,5-dioxo-1-pyrrolidinecarboxylate (CAS 25543-13-9)
Recommended Standards
- 2-(((3-Carboxyoxazolidin-5-yl)oxy)carbonyl)oxazolidine-3-carboxylic acid (CAS 62935-85-7)
- 4-Hydroxy-2,5-dioxoimidazolidine-4-carboxamide (CAS 36597-25-8)
- 1,3-Diamino-1,3,5-triazinane-2,4,6-trione (CAS 206279-61-0)
- 4-Hydroxy-5-methyl-3-nitrofuran-2(5H)-one (CAS 855457-67-9)
- 3-(Cyclopropylsulfonyl)pyrazolo[1,5-a]pyrimidin-6-amine (CAS 1707603-34-6)
- Ethyl 4-hydroxy-1-isobutyl-2-oxo-1,2-dihydroquinoline-3-carboxylate (CAS 303776-43-4)
- 3-(benzylamino)oxetane-3-carboxylic acid (CAS 1159738-31-4)
- 2-Butyramido-3-oxopropanoic acid (CAS 857210-78-7)
- (4,4-Difluoro-1-(pyridin-4-ylmethyl)cyclohexyl)methanamine dihydrochloride (CAS 1989793-11-4)
- 5-Hexyl-7-(S-methylsulfonimidoyl)-9-oxo-9H-xanthene-2-carboxylic acid (CAS 58761-87-8)
- ethyl (2Z)-2-cyano-3-(3,4-dihydro-2H-1,5-benzodioxepin-7-ylamino)prop-2-enoate (CAS 1181463-90-0)
- 5-Oxo-1-(pyridin-2-yl)pyrrolidine-2-carboxylic acid (CAS 2089674-26-8)
- 1-Phenyl-3-(propan-2-yl)-1h-pyrazole-4-carboxylic acid (CAS 1003577-72-7)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
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