4-Chloro-N,N-diethylquinazolin-2-amine CAS 78490-71-8
| CAS No. | 78490-71-8 |
| Molecular Formula | C12H14ClN3 |
| Molecular Weight | 235.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 235.71 g/mol gives 4-Chloro-N,N-diethylquinazolin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-N,N-diethylquinazolin-2-amine (CAS 78490-71-8) is a high-purity analytical reference standard with the molecular formula C12H14ClN3 and a molecular weight of 235.71 g/mol.
Structurally, 4-Chloro-N,N-diethylquinazolin-2-amine (C12H14ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 235.71 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-N,N-diethylquinazolin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14ClN3 |
| Molecular Weight | 235.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-N,N-diethylquinoxalin-2-amine (CAS 100116-89-0)
- 1-(2-Chloro-5,7-dimethylquinolin-3-yl)ethanol (CAS 1017402-93-5)
- 1-(2-Chloro-6,8-dimethylquinolin-3-yl)ethanol (CAS 1017402-97-9)
- 1-(2-Chloro-6-ethylquinolin-3-yl)ethanol (CAS 1017403-12-1)
- 1-(2-Chloro-7,8-dimethylquinolin-3-yl)ethanol (CAS 1017403-18-7)
- (2-Chloro-8-isopropylquinolin-3-yl)methanol (CAS 1017403-75-6)
- 1-(2-Chloro-8-ethylquinolin-3-yl)ethanol (CAS 1017428-71-5)
- 1-(2-Chloro-5,8-dimethylquinolin-3-yl)ethanol (CAS 1017463-30-7)
Recommended Standards
- 4-Chloro-N,N-diethylphthalazin-1-amine (CAS 496028-43-4)
- 4'-Hydroxychlorpropham (CAS 28705-96-6)
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- 4-Sulfamoylbutane-1-sulfonyl chloride (CAS 2089254-97-5)
- DL-5-Hydroxylysine hydrochloride (CAS 13204-98-3)
- N-(Octahydro-2H-quinolizin-1-ylmethyl)butan-1-amine dihydrochloride (CAS 1803595-61-0)
- Corticotropin (R054N1) (CAS 9002-60-2)
- 3-Methyl-4-propoxy-N-(pyridin-3-ylmethyl)benzenesulfonamide (CAS 898650-46-9)
- Methyl 1-(4-chloro-1H-pyrrolo[2,3-b]pyridin-1-yl)cyclopentane-1-carboxylate (CAS 1638761-57-5)
- 4-Methylhexanenitrile (CAS 69248-32-4)
- 2-amino-1-(4-bromophenyl)-2-methylpropan-1-ol hydrochloride (CAS 1461706-69-3)
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- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com