2,4-Dichloro-6-phenyl-5-pyrimidinecarbonitrile CAS 78494-42-5
| CAS No. | 78494-42-5 |
| Molecular Formula | C11H5Cl2N3 |
| Molecular Weight | 250.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,4-Dichloro-6-phenyl-5-pyrimidinecarbonitrile (CAS 78494-42-5), a certified reference material (molecular formula C11H5Cl2N3, MW 250.08 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 2,4-Dichloro-6-phenyl-5-pyrimidinecarbonitrile is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 250.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,4-Dichloro-6-phenyl-5-pyrimidinecarbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H5Cl2N3 |
| Molecular Weight | 250.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloro Standards
- 5,6-Dichloro-[2,3'-bipyridine]-3-carbonitrile (CAS 1774900-99-0)
- 2,3-Dichloro-1-nitro-4-(propan-2-yloxy)benzene (CAS 1881322-37-7)
- 2,3-Dichloro-1-nitro-4-propoxybenzene (CAS 1881332-22-4)
- 1,3-Dichloro-2-ethoxy-5-methyl-4-nitrobenzene (CAS 67828-38-0)
- 1,3-Dichloro-5-nitro-2-(propan-2-yloxy)benzene (CAS 57715-89-6)
- 1,3-Dichloro-5-nitro-2-propoxybenzene (CAS 90650-27-4)
- 1,5-Dichloro-2-isopropoxy-4-nitrobenzene (CAS 41200-97-9)
- 3,5-Dichloro-6-(2-hydroxypropan-2-yl)pyrazine-2-carboxamide (CAS 313339-98-9)
Recommended Standards
- 2-(Ethoxycarbonyl)-1-benzothiophene-4-boronic acid (CAS 2377611-46-4)
- 2-Butyl-5-iodofuran (CAS 558472-48-3)
- 1-Butyl-4-iodo-1H-pyrazole (CAS 918487-10-2)
- 3,5-Diethyl-4-iodo-1h-pyrazole (CAS 390356-27-1)
- 5-((3-Nitro-1h-pyrazol-1-yl)methyl)thiophene-2-carboxylic acid (CAS 1006457-74-4)
- 1-Benzoyl-1,2-dihydroquinoline-2-carbonitrile (CAS 13721-17-0)
- 1,3-Dimethoxyisoquinoline (CAS 87954-17-4)
- Diphenyl(4-phenylthio)phenylsufonium hexafluorophosphate (CAS 68156-13-8)
- 1-(2-Hydroxy-5-(hydroxymethyl)phenyl)ethanone (CAS 31611-90-2)
- 2-Chloro-4-fluoro-1-(trifluoromethoxy)benzene (CAS 1404194-16-6)
- 7,7-Bis(4-(dibutylamino)-2-ethoxyphenyl)furo[3,4-b]pyrazin-5(7H)-one (CAS 188610-60-8)
- [Methyl-(1-methyl-piperidin-4-yl)-amino]-acetic acid (CAS 876710-43-9)
- 1-BOC-3-[hydroxy(thiophen-2-yl)methyl]indole (CAS 1423037-53-9)
- Calcitonin C-Terminal Flanking Peptide (human) XTFA (CAS 85916-47-8（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com