4-(Bromomethyl)-2-phenylthiazole CAS 78502-83-7
| CAS No. | 78502-83-7 |
| Molecular Formula | C10H8BrNS |
| Molecular Weight | 254.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Bromomethyl)-2-phenylthiazole.
CATO supplies 4-(Bromomethyl)-2-phenylthiazole (CAS 78502-83-7), a certified reference material (molecular formula C10H8BrNS, MW 254.15 g/mol) for analytical method development and quality control.
The molecular framework of 4-(Bromomethyl)-2-phenylthiazole (C10H8BrNS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Bromomethyl)-2-phenylthiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8BrNS |
| Molecular Weight | 254.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromomethyl Standards
- 2-(4-(Bromomethyl)phenyl)thiazole (CAS 1187451-26-8)
- 2-(Bromomethyl)-4-phenylthiazole (CAS 78502-79-1)
- 5-(Bromomethyl)-3-phenylisothiazole (CAS 2102086-01-9)
- 1-Benzyl-2-(bromomethyl)pyrrolidine (CAS 1252879-81-4)
- 1-Benzyl-3-(bromomethyl)pyrrolidine (CAS 1260805-99-9)
- 6-(Bromomethyl)-1-methyl-1,2,3,4-tetrahydroquinolin-2-one (CAS 184636-25-7)
- Methyl 2-(bromomethyl)-6-cyanobenzoate (CAS 1022980-69-3)
- Methyl 3-(bromomethyl)-5-cyanobenzoate (CAS 1261878-67-4)
Recommended Standards
- 4-(4-Bromophenyl)-2-methylthiazole (CAS 66047-74-3)
- 4-Benzyl-2-bromothiazole (CAS 73553-79-4)
- 4-(3-Bromophenyl)-2-methylthiazole (CAS 342405-21-4)
- 4-Bromo-6-(methylthio)quinoline (CAS 933486-42-1)
- 3-(4,4,6-Trimethyl-2-thioxotetrahydropyrimidin-1(2H)-yl)propanoic acid (CAS 1017791-45-5)
- 1-(3-methoxyphenyl)pyrimidine-2,4,6(1h,3h,5h)-trione (CAS 192204-76-5)
- 2-(Naphthalen-1-ylamino)benzoic acid (CAS 13278-41-6)
- Tert-butyl 4-(4-fluorophenyl)-3-hydroxypiperidine-1-carboxylate (CAS 1187171-99-8)
- (1s)-1-(4,4-Dimethylcyclohexyl)ethan-1-ol (CAS 1423040-70-3)
- 1-(2-Nitrobenzyl)isoquinoline (CAS 17750-45-7)
- Ethyl 4-(3-chlorobenzoyl)isoxazole-3-carboxylate (CAS 338761-68-5)
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- 7-Acetyl-3-ethyl-1,5-naphthyridin-2(1H)-one (CAS 2851897-77-1)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
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