Di-tert-butyl Phosphorochloridite CAS 78543-77-8
| CAS No. | 78543-77-8 |
| Molecular Formula | C8H18ClO2P |
| Molecular Weight | 212.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Di-tert-butyl Phosphorochloridite (CAS 78543-77-8), a certified reference material (molecular formula C8H18ClO2P, MW 212.65 g/mol) for analytical method development and quality control.
Owing to organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Di-tert-butyl Phosphorochloridite is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 212.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Di-tert-butyl Phosphorochloridite under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H18ClO2P |
| Molecular Weight | 212.65 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | -0.5 |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com