Methyl 5-bromo-6-chloropyridine-3-carboxylate CAS 78686-77-8
| CAS No. | 78686-77-8 |
| Molecular Formula | C7H5BrClNO2 |
| Molecular Weight | 250.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 5-bromo-6-chloropyridine-3-carboxylate.
CATO supplies Methyl 5-bromo-6-chloropyridine-3-carboxylate (CAS 78686-77-8), a certified reference material (molecular formula C7H5BrClNO2, MW 250.48 g/mol) for analytical method development and quality control.
Structurally, Methyl 5-bromo-6-chloropyridine-3-carboxylate (C7H5BrClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 250.48 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 5-bromo-6-chloropyridine-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BrClNO2 |
| Molecular Weight | 250.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- Methyl 5-Bromo-2-chloronicotinate (CAS 78686-79-0)
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- 2,4-Bis(4-bromophenyl)-6-chloro-1,3,5-triazine (CAS 754980-62-6)
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