5-bromo-2-chloro-pyridine-3-carbonyl chloride CAS 78686-86-9
| CAS No. | 78686-86-9 |
| Molecular Formula | C6H8BrCl2NO |
| Molecular Weight | 260.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-bromo-2-chloro-pyridine-3-carbonyl chloride (C6H8BrCl2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-bromo-2-chloro-pyridine-3-carbonyl chloride (CAS 78686-86-9), molecular formula C6H8BrCl2NO and molecular weight 260.94 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8BrCl2NO |
| Molecular Weight | 260.94 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related bromo Standards
- (6-bromo-2-naphthyl)boronic acid (CAS 1337916-18-3)
- (8-bromo-1-naphthyl)boronic acid (CAS 167105-03-5)
- 1-Bromo-4-selenocyanatobenzene (CAS 32449-46-0)
- 2-Bromo-1,5-difluoro-3-(trifluoromethyl)benzene (CAS 1099597-86-0)
- 1-Bromo-4,5-difluoro-2-(trifluoromethyl)benzene (CAS 112290-04-7)
- 2-Bromo-1,4-difluoro-3-(trifluoromethyl)benzene (CAS 1242339-93-0)
- 3-Bromo-2,6-difluorobenzotrifluoride (CAS 1263377-74-7)
- 2-Bromo-1,3-difluoro-4-(trifluoromethyl)benzene (CAS 1805023-67-9)
Recommended Standards
- 2-Chloro-6-methoxy-4-(trichloromethyl)pyridine (CAS 7159-34-4)
- 3,5-Dibromobenzonitrile (CAS 97165-77-0)
- 2,6-Dibromobenzonitrile (CAS 6575-12-8)
- 2-(Bromomethyl)-1,1,1,3,3,3-hexafluoropropan-2-ol (CAS 503169-76-4)
- Barium, [carbonato(2-)-O]- (CAS 784985-36-0)
- Thiophene-3-carbaldehyde oxime (CAS 42466-50-2)
- 4-(Acetylmethylamino)-1-(3-pyridyl)-1-butanol 4-(Acetylmethylamino)-1-(3-pyridyl)-1-butanol-d6 887352-16-1 N-(4-Hydroxy-4-pyridin-3-yl-butyl)-N-methyl-acetamide N-(4-Hydroxy-4-pyridin-3-yl-butyl)-N-methyl-acetamide-d6 (CAS 887352-16-1)
- 2,2,2-Trifluoroethyl ((tetrahydrofuran-2-yl)methyl)carbamate (CAS 1197504-90-7)
- 4-Hydroxy-2-naphthoic Acid (CAS 1573-91-7)
- N-[(2-bromophenyl)methyl]-2-cyanoacetamide (CAS 566926-28-1)
- 2-(tert-Butyl)-5-methyl-1,3,4-thiadiazole (CAS 38391-22-9)
- [4-(sec-Butoxy)phenyl]-N-(tetrahydro-2-furanylmethyl)methanamine (CAS 1040680-59-8)
- Tert-butyl ((1r,3r)-3-ethynylcyclobutyl)carbamate (CAS 2427585-76-8)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com