Econazole impurity 22 CAS 787501-56-8
| CAS No. | 787501-56-8 |
| Molecular Formula | C19H17Cl4N2O2 |
| Molecular Weight | 447.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Econazole impurity 22 (CAS 787501-56-8), a pharmacopoeial impurity reference standard (molecular formula C19H17Cl4N2O2, MW 447.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H17Cl4N2O2, Econazole impurity 22 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 447.16 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Econazole impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H17Cl4N2O2 |
| Molecular Weight | 447.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Econazole Standards
- Econazole-d6 (CAS CATO-CCAD304748)
- Econazole (CAS 27220-47-9)
- Econazole impurity 25 (CAS CATO-C4X-132725)
- Econazole impurity 23 (CAS 1165796-83-7)
- Econazole impurity 24 (CAS 2237961-00-9)
- Econazole EP Impurity B (CAS 2334059-11-7)
- Econazole impurity 28 (CAS 56719-70-1)
- Econazole impurity 19 (CAS 27523-08-6)
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