6-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione CAS 78755-95-0
| CAS No. | 78755-95-0 |
| Molecular Formula | C10H9FN2O2 |
| Molecular Weight | 208.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione.
6-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione (CAS 78755-95-0), molecular formula C10H9FN2O2 and molecular weight 208.19 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C10H9FN2O2, 6-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 208.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9FN2O2 |
| Molecular Weight | 208.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- Ethyl 5-fluoro-1H-indazole-3-carboxylate (CAS 1016-36-0)
- Methyl 4-fluoro-1-oxo-2,3-dihydro-1h-indene-2-carboxylate (CAS 1071727-59-7)
- 3-Fluoro-5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid (CAS 1092348-21-4)
- 5-[(3-fluoro-4-methoxyphenyl)methyl]-1h-1,2,3,4-tetrazole (CAS 1094350-33-0)
- 2-(3-Fluoro-4-methoxyphenyl)-5-methyl-1,3,4-oxadiazole (CAS 1171931-54-6)
- 3-(4-fluoro-1H-1,3-benzodiazol-2-yl)propanoic acid (CAS 1183522-97-5)
- 5-(3-Fluoro-4-methoxyphenyl)isoxazol-3-amine (CAS 1268097-76-2)
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Recommended Standards
- 6-Fluoro-2,3-dimethyl-2H-indazole-5-carboxylic acid (CAS 2407081-84-7)
- 6-Nitrobenzo[d]thiazole-2-carbaldehyde (CAS 831-44-7)
- 6-(1,3-Dioxolan-2-yl)-2-fluorobenzofuran (CAS 648915-97-3)
- Diethyl ((allyloxy)methyl)phosphonate (CAS 64226-00-2)
- 39391-39-4 R76HLW7Z19 Nocardicin A 1-Azetidineacetic acid, 3-(((4-(3-amino-3-carboxypropoxy)phenyl)(hydroxyimino)acetyl)amino)-alpha-(4-hydroxyphenyl)-2-oxo-, (3S-(1(S*),3R*(Z(S*))))- Antibiotic FR 1923 FR-1923-C UNII-R76HLW7Z19 (CAS 39391-39-4)
- 2-Fluoro-5-methanesulfonylbenzene-1-sulfonyl chloride (CAS 1744-09-8)
- 1-(3,5-Difluorophenyl)prop-2-en-1-one (CAS 1491040-55-1)
- 2-(Bromomethyl)-5-cyclopropyloxazole (CAS 2323035-36-3)
- 4-Ethoxy-N-((1-(hydroxymethyl)cyclopropyl)methyl)benzamide (CAS 1323557-46-5)
- 1-(3-Chloro-2-fluorophenyl)ethanamine hydrochloride (CAS 1956371-30-4)
- 2-(2-Chlorophenoxy)aniline (CAS 56966-47-3)
- N-Methyl-3-(2-nitrophenoxy)-N-phenylthiophene-2-carboxamide (CAS 252027-05-7)
- DL-AP5 Sodium Salt (CAS 1303993-72-7)
- Peptide 46 (H-4054.0500) (CAS 192122-40-0)
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