Methyl 5-chloro-2-methoxy-4-(methylamino)benzoate CAS 78775-33-4
| CAS No. | 78775-33-4 |
| Molecular Formula | C10H12ClNO3 |
| Molecular Weight | 229.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 5-chloro-2-methoxy-4-(methylamino)benzoate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Methyl 5-chloro-2-methoxy-4-(methylamino)benzoate (CAS 78775-33-4), a certified reference material (molecular formula C10H12ClNO3, MW 229.66 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H12ClNO3, Methyl 5-chloro-2-methoxy-4-(methylamino)benzoate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 229.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO3 |
| Molecular Weight | 229.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 3-(4-Methoxyphenyl)-N-(prop-2-en-1-yl)-1,2-oxazole-5-carboxamide (CAS 477859-13-5)
- (1r,4r)-4-(((6-(1-(Cyclopropylmethyl)-2-oxo-1,2-dihydropyridin-4-yl)benzo[d]thiazol-2-yl)amino)methyl)cyclohexane-1-carboxylic acid (CAS 1800017-49-5)
- 1-(2-(Pyridin-2-yl)ethyl)-1H-pyrazol-4-amine (CAS 1183259-04-2)
- 6-Amino-5-nitrosouracil (CAS 5442-24-0)
- Ursodeoxycholic Acid Impurity 1 (CAS 4057-84-5)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
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