3-Chloro-2-nitrobenzenesulfonyl chloride CAS 78846-40-9
| CAS No. | 78846-40-9 |
| Molecular Formula | C6H3Cl2NO4S |
| Molecular Weight | 256.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-2-nitrobenzenesulfonyl chloride (CAS 78846-40-9) is a high-purity analytical reference standard with the molecular formula C6H3Cl2NO4S and a molecular weight of 256.06 g/mol.
Structurally, 3-Chloro-2-nitrobenzenesulfonyl chloride (C6H3Cl2NO4S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 256.06 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3Cl2NO4S |
| Molecular Weight | 256.06 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-3-nitrobenzenesulfonyl chloride (CAS 15945-25-2)
- 2-Chloro-6-nitrobenzene-1-sulfonyl chloride (CAS 17970-75-1)
- 2-Chloro-4-nitrobenzenesulfonyl Chloride (CAS 20201-03-0)
- 2-Chloro-5-(chlorosulfonyl)nicotinic acid (CAS 476156-65-7)
- 2-Chloro-5-nitrobenzenesulfonyl Chloride (CAS 4533-95-3)
- 3-Chloro-4-nitrobenzenesulfonyl Chloride (CAS 64835-30-9)
- 3-Chloro-5-nitrobenzenesulfonyl chloride (CAS 953891-33-3)
- 4-Chloro-3-nitrobenzenesulfonyl Chloride (CAS 97-08-5)
Recommended Standards
- 3-Bromo-6-methyl-4-nitro-1H-indazole (CAS 885520-86-5)
- 3-Bromo-5-methyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid (CAS 2167720-77-4)
- 3-Bromo-2-methyl-6-nitro-2H-indazole (CAS 74209-41-9)
- 4’-(Methoxycarbonyl)biphenyl-4-boronic Acid (CAS 501944-43-0)
- 2-methylpyrazole-3-carbonyl chloride (CAS 84547-59-1)
- D-beta-Tocotrienol (CAS 490-23-3)
- Imidodicarbonic acid, (2-bromo-4-fluoro-6-nitrophenyl)-, bis(1,1-dimethylethyl) ester (CAS 880384-52-1)
- 2-((2,6-Dichlorophenyl)thio)-1,1-diphenylethan-1-ol (CAS 252026-42-9)
- 5-Bromo-2,3-dimethylpyridine (CAS 27063-90-7)
- 9-Aminominocycline Epimer (CAS CATO-C4X-169920)
- 2-(2,3-dimethylphenyl)-2-(trifluoromethyl)pyrrolidine (CAS 1384431-01-9)
- 2-Oxo-4-phenyl-2,5-dihydrofuran-3-carbonitrile (CAS 7692-89-9)
- 3-(trideuteriomethoxy)propan-1-amine (CAS 2790397-48-5)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com