4-(4-Bromophenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid CAS 78860-79-4
| CAS No. | 78860-79-4 |
| Molecular Formula | C18H14BrNO3 |
| Molecular Weight | 372.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-(4-Bromophenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-(4-Bromophenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid (CAS 78860-79-4), molecular formula C18H14BrNO3 and molecular weight 372.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4-Bromophenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid (C18H14BrNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14BrNO3 |
| Molecular Weight | 372.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromophenyl Standards
- Ethyl 3-((1-(4-bromophenyl)-3-methoxy-3-oxopropyl)amino)-3-oxopropanoate (CAS 383147-00-0)
- N-(2-Bromophenyl)-2-((2-methylquinazolin-4-yl)oxy)acetamide (CAS 1003182-72-6)
- N-(2-Bromophenyl)-5-cyano-2-phenylisoxazolidine-3-carboxamide (CAS 62513-15-9)
- 1-(4-Bromophenyl)-3-((4-(trifluoromethyl)phenyl)amino)propan-1-one (CAS 477334-28-4)
- 1-(4-Bromophenyl)-3-(3-nitrophenyl)-1H-pyrazole-4-carbaldehyde (CAS 618099-03-9)
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- 3-(3-Bromophenyl)-2-((tert-butoxycarbonyl)amino)pentanoic acid (CAS 2139153-76-5)
Recommended Standards
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(3-(trifluoromethyl)phenyl)thiophen-2-yl)boronate (CAS 2223011-20-7)
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- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(2-(trifluoromethyl)phenyl)thiophen-2-yl)boronate (CAS 2223042-41-7)
- 6-Bromo-2-(3-ethoxyphenyl)quinoline-4-carboxylic acid (CAS 350999-95-0)
- 2,6-Dichloro-4-(difluoromethoxy)benzaldehyde (CAS 1804936-61-5)
- 5-Chloro-6-nitrobenzo[d]thiazole (CAS 85123-28-0)
- 5-(Morpholin-4-ylmethyl)pyridin-2-amine (CAS 400775-78-2)
- Methyl 3-oxo-3-(thiophen-3-yl)propanoate (CAS 185515-21-3)
- 2-(3,5-Dimethyl-1h-pyrazol-1-yl)ethan-1-amine dihydrochloride (CAS 1185304-68-0)
- N-(4-(N-Cyclopropylsulfamoyl)phenyl)acetamide (CAS 355001-37-5)
- tert-Butyl 3-amino-3-carbamoylazetidine-1-carboxylate hydrochloride (CAS 2055839-99-9)
- exo-8-Boc-8-azabicyclo[3.2.1]octan-2-amine (CAS 1408074-65-6)
- 3-(Difluoromethyl)-5-((4-methoxy-2-nitrophenyl)thio)-4H-1,2,4-triazole (CAS 1706450-48-7)
- Tau Peptide (294-305) (human) trifluoroacetate salt (CAS 1428135-29-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com