Cariprazine Impurity 1 CAS 791778-53-5
| CAS No. | 791778-53-5 |
| Molecular Formula | C18H27Cl2N3 |
| Molecular Weight | 356.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Cariprazine Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Cariprazine Impurity 1 (CAS 791778-53-5), a pharmacopoeial impurity reference standard (molecular formula C18H27Cl2N3, MW 356.33 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Cariprazine Impurity 1 (C18H27Cl2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H27Cl2N3 |
| Molecular Weight | 356.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Cariprazine Standards
- Cariprazine Impurity 22 (CAS 1480744-31-7)
- Cariprazine Impurity 35 (CAS CATO-C4X-240835)
- Cariprazine Impurity 66 (CAS CATO-C4X-240866)
- Cariprazine Impurity 49 (CAS CATO-C4X-240849)
- Cariprazine Impurity 53 (CAS CATO-C4X-240853)
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- Cariprazine Impurity 13 (CAS 1698050-46-2)
- Cariprazine Impurity 21 (CAS CATO-C4X-240821)
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Why CATO?
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