Methyl 2-(2-chloro-7-methoxyquinolin-3-yl)acetate CAS 79249-35-7
| CAS No. | 79249-35-7 |
| Molecular Formula | C13H12ClNO3 |
| Molecular Weight | 265.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 2-(2-chloro-7-methoxyquinolin-3-yl)acetate (C13H12ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Methyl 2-(2-chloro-7-methoxyquinolin-3-yl)acetate (CAS 79249-35-7) is a high-purity analytical reference standard with the molecular formula C13H12ClNO3 and a molecular weight of 265.69 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2-(2-chloro-7-methoxyquinolin-3-yl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12ClNO3 |
| Molecular Weight | 265.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl 2-(4-chloro-7-methoxyquinolin-2-yl)acetate (CAS 1017403-04-1)
- 3-Chloro-2-(2-methoxyethyl)-1-oxo-isoquinoline-4-carbaldehyde (CAS 1018566-34-1)
- 7-Chloro-5-(4-fluorophenyl)thiazolo[4,5-d]pyrimidine (CAS 1043931-29-8)
- 5-Chloro-N-(2-(furan-2-yl)ethyl)-2-hydroxybenzamide (CAS 1060971-98-3)
- 2-chloro-N-(2-fluoro-5-methanesulfonylphenyl)acetamide (CAS 1153346-21-4)
- Ethyl 6-chloro-2-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 120420-51-1)
- 2-chloro-N-(2-acetyl-1-benzofuran-3-yl)propanamide (CAS 1208828-89-0)
- Methyl 3-(6-chloro-4-oxoquinolin-1(4H)-yl)propanoate (CAS 1279212-97-3)
Recommended Standards
- Ethyl 8-chloro-7-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 6291-29-8)
- Methyl 2-chloro-8-methoxy-3-methylquinoline-6-carboxylate (CAS 2734048-70-3)
- Ethyl 8-chloro-4-hydroxy-6-methylquinoline-3-carboxylate (CAS 338795-13-4)
- Methyl 4-(4-(chloromethyl)-5-methyloxazol-2-yl)benzoate (CAS 675148-38-6)
- 2,8-Dichloro-6-fluoroquinoline (CAS 1342015-45-5)
- 3-(Cyclohexylmethyl)-8,9-dimethoxy-5-{[(4-methylphenyl)methyl]sulfanyl}-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 1031207-64-3)
- Boc-Glu-OcHex (CAS 137506-13-9)
- Exemestane Impurity 31 (CAS 26991-58-2)
- Isoquinolin-8-amine dihydrochloride (CAS 1187929-16-3)
- 1H-Pyrrole-2-carboxylic acid, 5-(2-imidazo[1,2-a]pyridin-5-ylethynyl)-1-methyl- (CAS 2549239-50-9)
- N-(2,3-Dihydroxypropyl)-4-(2-(5-nitrofuran-2-yl)vinyl)benzamide (CAS 61470-58-4)
- 3,4-Difluoro-5-methylphenylacetonitrile (CAS 1806289-81-5)
- 5-(Prop-1-yn-1-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 1425411-71-7)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
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