Dimethyl 2,3-difluorofumarate CAS 79322-43-3

Purity 97%+In StockPharmaceutical Standards
CAS No.79322-43-3
Molecular FormulaC6H6F2O4
Molecular Weight180.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Dimethyl 2,3-difluorofumarate CAS 79322-43-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 180.11 g/mol gives Dimethyl 2,3-difluorofumarate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Dimethyl 2,3-difluorofumarate (CAS 79322-43-3) is a high-purity analytical reference standard with the molecular formula C6H6F2O4 and a molecular weight of 180.11 g/mol.

Dimethyl 2,3-difluorofumarate (C6H6F2O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H6F2O4
Molecular Weight180.11 g/mol
Purity97%+
StorageStore at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1979
Halogen ContentF-containing

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