Cefixime EP Impurity F CAS 79368-95-9
| CAS No. | 79368-95-9 |
| Molecular Formula | C18H19N5O7S2 |
| Molecular Weight | 481.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Cefixime EP Impurity F (CAS 79368-95-9, C18H19N5O7S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Cefixime EP Impurity F (C18H19N5O7S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Cefixime EP Impurity F meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H19N5O7S2 |
| Molecular Weight | 481.50 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Cefixime Standards
- Cefixime Impurity 53 (CAS CATO-C4X-113953)
- Cefixime Impurity 76 (CAS CATO-C4X-113976)
- Cefixime Impurity 61 (CAS CATO-C4X-113961)
- Cefixime Impurity 52 (CAS CATO-C4X-113952)
- Cefixime Impurity 50 (CAS 2682217-22-5)
- Cefixime Impurity 88 (CAS CATO-C4X-113988)
- Cefixime Impurity 89 (CAS CATO-C4X-113989)
- Cefixime Impurity 90 (CAS CATO-C4X-113990)
Recommended Standards
- Tert-butyl 5-bromo-3-(((tert-butyldimethylsilyl)oxy)methyl)-7-cyano-3-methylindoline-1-carboxylate (CAS 2113619-01-3)
- Aztreonam Open-Ring Ethyl Ester (CAS CATO-C4X-152227)
- Tert-butyl (S)-5-bromo-3-(((tert-butyldimethylsilyl)oxy)methyl)-7-cyano-3-methylindoline-1-carboxylate (CAS 2113619-05-7)
- Aztreonam Impurity 44 (CAS CATO-C4X-152244)
- Lomefloxacin Impurity 5 TFA (CAS CATO-C4X-20735)
- Chlorhexidine Impurity 18 (CAS CATO-C4X-225618)
- Ixabepilone Impurity 4 (CAS 1220999-09-6)
- n-(Tert-butyl)-3-(2-fluorophenoxy)propanamide (CAS 1311810-78-2)
- 2-((2-Bromo-4-methylthiazol-5-yl)methyl)isoindoline-1,3-dione (CAS 1151512-21-8)
- 3-(1-Methylcyclohexyl)-1H-pyrazol-5-amine (CAS 110086-31-2)
- 1-Benzyl-2-oxopyrrolidine-3-carboxylic acid (CAS 109859-99-6)
- (R)-5-Hydroxy Propafenone Hydrochloride (CAS 158080-72-9)
- 2-(Pyrrolidin-1-yl)ethane-1-sulfonyl chloride (CAS 1174395-84-6)
- Rac1 Inhibitor F56, control peptide (CAS 1315378-77-8)
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