4-(Chloromethyl)-2-phenyl-1,3-thiazole hydrochloride CAS 79387-14-7
| CAS No. | 79387-14-7 |
| Molecular Formula | C10H8ClNS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Chloromethyl)-2-phenyl-1,3-thiazole hydrochloride (C10H8ClNSHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(Chloromethyl)-2-phenyl-1,3-thiazole hydrochloride (CAS 79387-14-7), molecular formula C10H8ClNSHCl and molecular weight 246.15 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Chloromethyl)-2-phenyl-1,3-thiazole hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNS HCl |
| Molecular Weight | 246.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloromethyl Standards
- 7-(Chloromethyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-81-4)
- 7-(Chloromethyl)-2,3-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-82-5)
- 7-(Chloromethyl)-3-(4-chlorophenyl)-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-85-8)
- chloromethyl 2-ethoxy-2-methylpropanoate (CAS 1000296-74-1)
- 5-(chloromethyl)-N-(4-methylbenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-24-0)
- 5-(Chloromethyl)-7-ethoxy-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1000932-47-7)
- 5-(chloromethyl)-N-(4-fluorobenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-60-4)
- 2-(Chloromethyl)-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine (CAS 1000933-67-4)
Recommended Standards
- 2-(4-Chlorophenyl)phenanthrene (CAS 2072093-50-4)
- 4,6-Bis(3,5-di(pyridin-4-yl)phenyl)-2-phenylpyrimidine (CAS 1097652-83-9)
- Diethyl 2-((3-chlorophenyl)amino)malonate (CAS 6626-01-3)
- 1-[4-(Trifluoromethoxy)phenyl]cyclopentanamine (CAS 1704079-01-5)
- (1-(4-Isopropylphenyl)cyclohexyl)methanamine (CAS 1037132-07-2)
- ((2R,3S,4S,5S,6S)-3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)methyl dihydrogen phosphate (CAS 40436-60-0)
- n-(1-Cyclohexyl-1h-pyrazol-3-yl)methanesulfonamide (CAS 1342011-91-9)
- 3-[(4-fluorophenyl)sulfamoyl]thiophene-2-carboxylic acid (CAS 944893-98-5)
- Ethyl 5-(3-(azetidin-1-ylmethyl)phenyl)-5-oxopentanoate (CAS 898772-48-0)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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