Lovastatin Impurity 7 CAS 79394-47-1
| CAS No. | 79394-47-1 |
| Molecular Formula | C19H28O3 |
| Molecular Weight | 304.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Lovastatin Impurity 7 (CAS 79394-47-1, C19H28O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lovastatin Impurity 7 (C19H28O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H28O3 |
| Molecular Weight | 304.42 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
Related Lovastatin Standards
- Lovastatin Impurity 22 (CAS CATO-C4X-168422)
- Lovastatin Impurity 14 (CAS CATO-C4X-168414)
- Lovastatin Impurity 8 (CAS 86827-77-2)
- Lovastatin Impurity 39 (CAS CATO-C4X-168439)
- Lovastatin Impurity 47 (CAS CATO-C4X-168447)
- Lovastatin Impurity 42 (CAS CATO-C4X-168442)
- Lovastatin Impurity 24 (CAS CATO-C4X-168424)
- Lovastatin Impurity 46 (CAS CATO-C4X-168446)
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