2,5-Diaminopyrimidin-4(3H)-one dihydrochloride CAS 79442-02-7
| CAS No. | 79442-02-7 |
| Molecular Formula | C4H6N4O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,5-Diaminopyrimidin-4(3H)-one dihydrochloride (C4H6N4OHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2,5-Diaminopyrimidin-4(3H)-one dihydrochloride (CAS 79442-02-7) is a high-purity analytical reference standard with the molecular formula C4H6N4OHCl and a molecular weight of 162.58 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H6N4O 2*HCl |
| Molecular Weight | 162.58 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Diaminopyrimidin Standards
- (2,4-Diaminopyrimidin-5-yl)boronic acid (CAS 1045861-29-7)
- 4,5-Diaminopyrimidin-2-ol (CAS 1071046-18-8)
- 1-(4,6-Diaminopyrimidin-5-yl)guanidine (CAS 107930-05-2)
- 1-(2,6-Diaminopyrimidin-4-yl)piperidin-3-ol (CAS 111152-92-2)
- Methyl 3-((4,6-diaminopyrimidin-2-yl)thio)propanoate (CAS 1147332-24-8)
- 2,5-Diaminopyrimidin-4(3H)-one sulfate (CAS 127726-94-7)
- 1,4-Diaminopyrimidin-2(1H)-one (CAS 137062-89-6)
- 2,4-diaminopyrimidin-5-ol dihydrochloride (CAS 141124-58-5)
Recommended Standards
- 2-(4,6-Dibromo-5-(difluoromethyl)pyridin-2-yl)acetonitrile (CAS 1805242-94-7)
- 5-Iodo-2-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1638771-62-6)
- 3-Cyclopropoxy-5-(methylthio)pyridin-4-amine (CAS 1243411-39-3)
- 2-Amino-5-chlorobenzothioamide (CAS 25465-36-5)
- BocNH-PEG8-CH2COOH (CAS 2147743-36-8)
- 1-{[2-(4-fluorophenyl)-1,3-thiazol-4-yl]methyl}piperazine hydrochloride (CAS 1251923-26-8)
- Tert-butyl1-acetyl-3-azabicyclo[3.1.0]hexane-3-carboxylate (CAS 2164962-36-9)
- 2-Amino-4-(4-chlorophenyl)-6-ethyl-5-methylnicotinonitrile (CAS 338794-05-1)
- Oxazole, 2,2′-[(phenylphosphinidene)di-2,1-phenylene]bis[4-(1,1-dimethylethyl)-4,5-dihydro-, (4S,4′S)- (CAS 642491-11-0)
- Biotinyl-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802086-28-7)
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