N-(5-Chloro-2-morpholinophenyl)-2-(methylthio)nicotinamide CAS 794580-12-4
| CAS No. | 794580-12-4 |
| Molecular Formula | C17H18ClN3O2S |
| Molecular Weight | 363.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 363.86 g/mol gives N-(5-Chloro-2-morpholinophenyl)-2-(methylthio)nicotinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(5-Chloro-2-morpholinophenyl)-2-(methylthio)nicotinamide (CAS 794580-12-4), molecular formula C17H18ClN3O2S and molecular weight 363.86 g/mol, is a CATO reference standard with documented purity and traceability.
N-(5-Chloro-2-morpholinophenyl)-2-(methylthio)nicotinamide (C17H18ClN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(5-Chloro-2-morpholinophenyl)-2-(methylthio)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H18ClN3O2S |
| Molecular Weight | 363.86 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- N-([1,1'-biphenyl]-2-yl)-3-chlorobenzo[b]thiophene-2-carboxamide (CAS 332156-26-0)
- Methyl 2-[(chloroacetyl)amino]-6-phenyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 905011-06-5)
- trans-δ2-11-methyl-Dodecenoic Acid (CAS 677354-24-4)
- 2-(2-Hydroxyprop-1-en-1-yl)quinolin-8-ol (CAS 496924-69-7)
- 2-(Benzyloxy)-1-bromo-3,5-bis(trifluoromethyl)benzene (CAS 2586126-89-6)
- N-Cyclohexyl-L-phenylalaninamide Mono(trifluoroacetate) (CAS 200274-80-2)
- Sodium 3,5-bis((tetradecyloxy)carbonyl)benzenesulfinate (CAS 155160-86-4)
- 1,3-Difluoro-2-iodo-4-(trifluoromethoxy)benzene (CAS 2384430-21-9)
- N-(1-(6-Methoxypyridin-3-yl)-3-oxo-3-((4-phenylbutyl)amino)prop-1-en-2-yl)benzamide (CAS 1015856-07-1)
- 7-Chloro-4-((4-chlorophenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]thiazine (CAS 338777-92-7)
- 2-(2-Isothiocyanatoethyl)tetrahydrofuran (CAS 1249941-39-6)
- Casein kinase II peptide Substrate (CAS 154444-98-1)
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