Ethyl 6,7,8-Trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate CAS 79660-46-1
| CAS No. | 79660-46-1 |
| Molecular Formula | C12H8F3NO3 |
| Molecular Weight | 271.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Ethyl 6,7,8-Trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 79660-46-1), a certified reference material (molecular formula C12H8F3NO3, MW 271.19 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 6,7,8-Trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 271.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Ethyl 6,7,8-Trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8F3NO3 |
| Molecular Weight | 271.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 5,6,7-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 836619-82-0)
- (S)-2,4,5-Trifluoro-N-(1,1,1-trifluoropropan-2-yl)benzamide (CAS 1637677-41-8)
- 2,2,2-Trifluoro-N-(4-(3-hydroxy-3-methylbut-1-yn-1-yl)phenyl)acetamide (CAS 158074-65-8)
- (3E)-1,1,1-Trifluoro-4-[(2-oxo-2-phenylethyl)amino]pent-3-en-2-one (CAS 339010-40-1)
- 2,2,2-Trifluoro-1-(6-hydroxy-2,2-dimethylquinolin-1(2H)-yl)ethanone (CAS 828938-86-9)
- 2,2,2-Trifluoro-1-(7-(oxiran-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (CAS 2126162-97-6)
- Ethyl 3,3,3-trifluoro-2-(1H-indol-3-yl)propanoate (CAS 250671-91-1)
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Recommended Standards
- Methyl 3-[2-(trifluoromethyl)phenyl]-1,2-oxazole-5-carboxylate (CAS 330558-52-6)
- Ethyl 4-hydroxy-2-(trifluoromethyl)quinoline-3-carboxylate (CAS 75999-59-6)
- Methyl 3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylate (CAS 924633-56-7)
- 8-Methoxy-3-(trifluoromethyl)quinoline-6-carboxylic acid (CAS 2639205-59-5)
- Ethyl 5-bromo-3-methyl-1H-pyrazole-4-carboxylate (CAS 2510868-39-8)
- (4S,5R)-4,5-Dihydroxy-6-(hydroxymethyl)-4,5-dihydropyridazin-3(2H)-one (CAS 291744-32-6)
- 2-Amino-4-methyl-5-(piperidine-1-carbonyl)thiophene-3-carbonitrile (CAS 313971-49-2)
- Maleic acid, ammonia salt (CAS 44742-89-4)
- 5-chloro-2-fluoro-1-methoxy-3-nitrobenzene (CAS 1881329-43-6)
- 3-[(2-Bromophenoxy)methyl]pyrrolidinehydrochloride (CAS 1220036-81-6)
- 1-(Pentan-3-yl)-1H-pyrazol-5-amine (CAS 90206-24-9)
- (2S)-4-bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]-Butanoic acid methyl ester (CAS 76969-87-4)
- 2-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-4(1H)-one (CAS 159639-80-2)
- Semaglutide impurity 68 (CAS CATO-C4X-222668)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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