Lenvatinib Impurity 6 CAS 796848-79-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.796848-79-8
Molecular FormulaC10H11ClN2O2
Molecular Weight226.66 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Lenvatinib Impurity 6 CAS 796848-79-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 226.66 g/mol gives Lenvatinib Impurity 6 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Lenvatinib Impurity 6 (CAS 796848-79-8), a pharmacopoeial impurity reference standard (molecular formula C10H11ClN2O2, MW 226.66 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C10H11ClN2O2, Lenvatinib Impurity 6 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 226.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H11ClN2O2
Molecular Weight226.66 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentCl-containing
Nitrogen Atoms2

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