3-Amino-4-hydroxy-N-phenylbenzenesulfonamide CAS 80-20-6
| CAS No. | 80-20-6 |
| Molecular Formula | C12H12N2O3S |
| Molecular Weight | 264.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Amino-4-hydroxy-N-phenylbenzenesulfonamide (CAS 80-20-6), a certified reference material (molecular formula C12H12N2O3S, MW 264.30 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 3-Amino-4-hydroxy-N-phenylbenzenesulfonamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 264.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12N2O3S |
| Molecular Weight | 264.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-4-phenoxybenzenesulfonamide (CAS 104272-77-7)
- 3-{[(4-Amino-4H-1,2,4-triazol-3-yl)thio]methyl}-4-methoxybenzaldehyde (CAS 1119449-74-9)
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- (Z)-2-amino-5-(3,4-dimethoxybenzylidene)thiazol-4(5H)-one 1198098-03-1 F1950-0211 (CAS 1198098-03-1)
- N-(2-Amino-2-oxoethyl)-1-methyl-3-(thiophen-2-yl)-1H-pyrazole-5-carboxamide (CAS 1219913-50-4)
- (5z)-2-Amino-5-(3,4-dimethoxybenzylidene)-1,3-thiazol-4(5h)-one (CAS 324046-38-0)
- 2-((4-Amino-5-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 573707-08-1)
- 2-(5-Amino-[1,3,4]thiadiazol-2-yl)-N-(4-methoxy-phenyl)-acetamide (CAS 878656-32-7)
Recommended Standards
- 3-acetyl-4-phenyl-pyrrole-1-sulfonamide (CAS 2172947-84-9)
- 4-((4-Methoxyphenyl)sulfonyl)phenol (CAS 98116-80-4)
- 3-{[4-Methyl-5-(4-pyridinyl)-4h-1,2,4-triazol-3-yl]sulfanyl}propanoic acid (CAS 838843-11-1)
- 4-((6-Methylbenzo[d]thiazol-2-yl)amino)-4-oxobutanoic acid (CAS 261505-37-7)
- 5-(Benzyloxy)-3-hydroxymethylpyridine (CAS 875755-69-4)
- 4-(5-(5-Hydroxy-3-phenyl-2l2-isoxazolidin-4-yl)penta-2,4-dien-1-ylidene)-3-phenyl-2l2-isoxazolidin-5-one (CAS 61389-30-8)
- 2-[2-(morpholin-4-yl)ethyl]-1h-1,3-benzodiazol-5-amine (CAS 1154393-99-3)
- 2-(Bromomethyl)-4-fluoro-3-iodo-1-nitrobenzene (CAS 2091653-09-5)
- 2-(4-Benzoylphenyl)-2-(4-fluorophenyl)acetonitrile (CAS 446275-89-4)
- 1-((5,6-Dimethyl-1H-benzo[d]imidazol-1-yl)methyl)-1H-benzo[d][1,2,3]triazole (CAS 305861-56-7)
- 3-(Difluoromethyl)-4,5-difluoropyridine-2-sulfonamide (CAS 1805243-80-4)
- Usnic acid (CAS 125-46-2)
- 2-Ethyl-1-(2-methylpiperazin-1-yl)hexan-1-one hydrochloride (CAS 1835435-66-9)
- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com