5Beta-Pregnane-3Alpha,20Alpha-Diol CAS 80-92-2

Purity >95%In StockPharmaceutical Standards
CAS No.80-92-2
Molecular FormulaC21H36O2
Molecular Weight320.51 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5Beta-Pregnane-3Alpha,20Alpha-Diol CAS 80-92-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5Beta-Pregnane-3Alpha,20Alpha-Diol.

5Beta-Pregnane-3Alpha,20Alpha-Diol (CAS 80-92-2) is a high-purity analytical reference standard with the molecular formula C21H36O2 and a molecular weight of 320.51 g/mol.

5Beta-Pregnane-3Alpha,20Alpha-Diol (C21H36O2) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H36O2
Molecular Weight320.51 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>95%
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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