Cholesterol EP Impurity A CAS 80-99-9

Description

Compared with other compounds in its class, the molecular weight of 386.65 g/mol gives Cholesterol EP Impurity A distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Cholesterol EP Impurity A (CAS 80-99-9) is a certified pharmaceutical impurity reference standard with the molecular formula C27H46O and a molecular weight of 386.65 g/mol.

Structurally, Cholesterol EP Impurity A (C27H46O) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 386.65 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Cholesterol EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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