4-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)morpholine CAS 801225-16-1

Purity 97%+In StockPharmaceutical Standards
CAS No.801225-16-1
Molecular FormulaC14H20FN3O3S
Molecular Weight329.39 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)morpholine CAS 801225-16-1 chemical structure

Description

The occurrence of 4-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)morpholine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)morpholine (CAS 801225-16-1) is a high-purity analytical reference standard with the molecular formula C14H20FN3O3S and a molecular weight of 329.39 g/mol.

The molecular framework of 4-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)morpholine (C14H20FN3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H20FN3O3S
Molecular Weight329.39 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

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