(5Z)-5-[(4-hydroxyphenyl)methylene]imidazolidine-2,4-dione CAS 80171-33-1
| CAS No. | 80171-33-1 |
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(5Z)-5-[(4-hydroxyphenyl)methylene]imidazolidine-2,4-dione (CAS 80171-33-1), molecular formula C10H8N2O3 and molecular weight 204.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (5Z)-5-[(4-hydroxyphenyl)methylene]imidazolidine-2,4-dione (C10H8N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 2 |
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Recommended Standards
- (4R,5R)-5-(Methoxycarbonyl)-2,2-dimethyl-1,3-dioxolane-4-carboxylic acid (CAS 67812-33-3)
- (6-Nitroquinolin-2-yl)methanol (CAS 889944-45-0)
- (2-oxochromen-3-yl) acetate (CAS 58983-26-9)
- (Difluoro(trimethylsilyl)methyl)phosphonic acid (CAS 913263-04-4)
- 3-(4-Chlorophenyl)-4-(methylthio)-1H-pyrrole-2,5-dione (CAS 398130-20-6)
- 898795-00-1 3-(2,5-Dimethylphenyl)-1-[4-(methylsulfanyl)phenyl]propan-1-one DTXSID90644730 (CAS 898795-00-1)
- 2-Methoxy-4-(trifluoromethoxy)benzyl bromide (CAS 886500-35-2)
- Methyl 1-((tert-butoxycarbonyl)amino)-3-(hydroxymethyl)cyclobutanecarboxylate (CAS 191110-93-7)
- 2-Isocyano-1-(1-piperidyl)ethanone (CAS 67434-28-0)
- Carbazochrome Impurity 1 (CAS CATO-C4X-22911)
- Ezetimibe Impurity 87 (CAS 1197343-07-9)
- 2-(3,4-Dimethoxyphenyl)-1-phenylethylamine (CAS 43071-00-7)
- tert-Butyl 1,1,4-trimethyl-1,2-dihydrobenzo[d][1,3]azasiline-3(4H)-carboxylate (CAS 2222440-53-9)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
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