2-((tert-Butyldimethylsilyl)oxy)phenol CAS 80180-46-7
| CAS No. | 80180-46-7 |
| Molecular Formula | C12H20O2Si |
| Molecular Weight | 224.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-((tert-Butyldimethylsilyl)oxy)phenol (C12H20O2Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-((tert-Butyldimethylsilyl)oxy)phenol (CAS 80180-46-7) is a high-purity analytical reference standard with the molecular formula C12H20O2Si and a molecular weight of 224.37 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-((tert-Butyldimethylsilyl)oxy)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H20O2Si |
| Molecular Weight | 224.37 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
Related tert Standards
- 3-((tert-Butyldimethylsilyl)oxy)phenol (CAS 161006-18-4)
- 5-((Tert-butyldimethylsilyl)oxy)pyridin-2-amine (CAS 2201058-78-6)
- 1-((tert-Butyldimethylsilyl)oxy)-3-chloropropan-2-ol (CAS 136917-95-8)
- 3-((tert-Butyldimethylsilyl)oxy)-1,1-difluoropropan-2-amine (CAS 1822830-20-5)
- 4-((tert-Butyldimethylsilyl)oxy)aniline (CAS 111359-74-1)
- 3-((tert-Butyldimethylsilyl)oxy)aniline (CAS 121942-75-4)
- 2-((tert-Butyldimethylsilyl)oxy)aniline (CAS 69589-21-5)
- 5-((tert-Butyldimethylsilyl)oxy)-2-methylpyridine (CAS 215232-65-8)
Recommended Standards
- 1-Methyl-N-(2-(thiophen-2-yl)ethyl)piperidin-4-amine (CAS 933737-47-4)
- 2-(1-Azepanyl)-2-(2-thienyl)ethylamine (CAS 889939-37-1)
- 1-(1-Methylpiperidin-4-yl)-N-(thiophen-3-ylmethyl)methanamine (CAS 933722-40-8)
- 2-(4-Methylpiperidin-1-yl)-2-(thiophen-2-yl)ethan-1-amine (CAS 791079-98-6)
- [2-(2-Thienyl)-1,3-thiazol-4-yl]methanol (CAS 54986-94-6)
- 2-(tert-Butoxycarbonyl)isoindoline-5,6-dicarboxylic acid (CAS 1824411-98-4)
- Ethyl 2-(Chloromethyl)thiazole-4-carboxylate (CAS 842130-48-7)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
- 2-(6-Chloro-5-methylpyridin-3-yl)acetic acid (CAS 1000546-06-4)
- 4-(3,4-Dichlorophenoxy)aniline (CAS 67651-53-0)
- 2-(Piperazin-1-ylmethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin+ (CAS 1172909-05-5)
- 1-Chloro-2-(methoxymethyl)benzene (CAS 59579-08-7)
- 2-Ethylhexyl vinyl ether (CAS 103-44-6)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com