2-Phenyl-4-(2-(piperidin-4-yl)ethyl)quinoline hydrochloride CAS 80221-58-5
| CAS No. | 80221-58-5 |
| Molecular Formula | C22H24N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Phenyl-4-(2-(piperidin-4-yl)ethyl)quinoline hydrochloride (CAS 80221-58-5) is a high-purity analytical reference standard with the molecular formula C22H24N2HCl and a molecular weight of 352.91 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 2-Phenyl-4-(2-(piperidin-4-yl)ethyl)quinoline hydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 352.91 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H24N2 HCl |
| Molecular Weight | 352.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Phenyl Standards
- 1000339-76-3 Ethyl 2-(Piperidin-1-yl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ethyl 2-(piperidin-1-yl)-4-trifluoromethyl-1,3-thiazole-5-carboxylate ethyl 2-piperidin-1-yl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate (CAS 1000339-76-3)
- 2-(Piperidin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylic acid (CAS 1000339-77-4)
- Benzyl 2-(piperidin-4-yl)acetate hydrochloride (CAS 1000872-47-8)
- n-(Piperidin-3-ylmethyl)morpholine-4-carboxamide (CAS 1000941-33-2)
- 1000958-55-3 4-Ethyl-1-[2-(piperidin-4-yl)ethyl]piperidine DTXSID60649257 (CAS 1000958-55-3)
- 5-(Piperidin-2-yl)pyridin-2-amine (CAS 100133-12-8)
- 5-(Piperidin-1-ylmethyl)pyrimidine-2,4(1H,3H)-dione (CAS 100133-53-7)
- 1-methyl-5-(piperidin-1-ylcarbonyl)-1H-pyrazol-4-amine (CAS 1001500-82-8)
Recommended Standards
- 1-(Cyclohexylmethyl)pyrrolidine-3-carboxylic acid (CAS 1342104-96-4)
- Benzonitrile, 5-bromo-2-(difluoromethoxy)- (CAS 1261859-60-2)
- 3-Bromo-2-methylbenzo[b]thiophene (CAS 10243-15-9)
- 5,6-Diamino-2-(methylamino)pyrimidin-4(1H)-one (CAS 61693-25-2)
- [5-(4-methoxyphenyl)-1H-1,2,4-triazol-3-yl]methanamine hydrochloride (CAS 1258650-54-2)
- Ethyl 6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 950726-72-4)
- 2-Chlorobenzyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)propanoate (CAS 339010-48-9)
- 6-Hydroxy-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carbonitrile (CAS 450842-75-8)
- Tert-butyl 2-[(oxan-4-yl)amino]acetate (CAS 1178247-06-7)
- Acetyl Tetrapeptide-5 (CAS 820959-17-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com