Deoxycholic acid Impurity 8 CAS 80225-61-2
| CAS No. | 80225-61-2 |
| Molecular Formula | C25H42O4 |
| Molecular Weight | 406.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Deoxycholic acid Impurity 8.
Deoxycholic acid Impurity 8 (CAS 80225-61-2) is a certified pharmaceutical impurity reference standard with the molecular formula C25H42O4 and a molecular weight of 406.60 g/mol.
Deoxycholic acid Impurity 8 (C25H42O4) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H42O4 |
| Molecular Weight | 406.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
Related Deoxycholic Standards
- Deoxycholic acid impurity 93 (CAS 96840-44-7)
- Deoxycholic acid Impurity 12 (CAS 2024612-47-1)
- Deoxycholic acid Impurity 13 (CAS CATO-C4X-335913)
- Deoxycholic acid Impurity 22 (CAS 3360-89-2)
- Deoxycholic acid Impurity 6 (CAS 10544-23-7)
- Deoxycholic acid Impurity 7 (CAS 13002-75-0)
- Deoxycholic Acid-d5 (CAS 52840-14-9)
- Deoxycholic-2,2,4,4-d4 Acid (CAS 112076-61-6)
Recommended Standards
- Dodecyl pentaethylene glycolether (CAS 3055-95-6)
- Oseltamivir Impurity 69 (CAS CATO-C4X-172069)
- N1,N1'-(Anthracene-9,10-diylbis(methylene))bis(N1,N2,N2-trimethylethane-1,2-diamine) (CAS 106712-13-4)
- Oseltamivir Impurity 151 (CAS 651324-06-0)
- Methylprednisolone Acetate EP Impurity A (Mixture of Diastereomers) (CAS 151003-82-6)
- Dobutamine Impurity 32 (CAS CATO-C4X-129832)
- Fluticasone Impurity 42 (CAS CATO-C4X-165042)
- Potassium fluoroaluminate-AR (CAS 13775-52-5)
- 1-(6-Methyl-5,6,7,8-tetrahydrocinnolin-3-yl)piperidine-3-carboxylic acid (CAS 1707668-00-5)
- 7-Chloro-6-methyl-1,3,4,5-tetrahydrobenzo[b][1,6]naphthyridin-10(2H)-one (CAS 1338658-76-6)
- (R)-1-(4-bromophenyl)pentan-1-amine (CAS 1228542-91-3)
- (1-methyl-3-nitro-1H-pyrazol-4-yl)methanol (CAS 64182-20-3)
- 3-Cyclopropoxy-5-methoxyaniline (CAS 1243383-76-7)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
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