7-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile CAS 80231-67-0

Purity 97%+In StockPharmaceutical Standards
CAS No.80231-67-0
Molecular FormulaC11H8N2O
Molecular Weight184.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile CAS 80231-67-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 184.19 g/mol gives 7-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

7-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile (CAS 80231-67-0), molecular formula C11H8N2O and molecular weight 184.19 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 7-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile (C11H8N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 7-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H8N2O
Molecular Weight184.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Nitrogen Atoms2

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