5-acetyl-1H-pyrrole-3-carbonitrile CAS 80242-22-4

Purity 97%+In StockPharmaceutical Standards
CAS No.80242-22-4
Molecular FormulaC7H10N2O
Molecular Weight138.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-acetyl-1H-pyrrole-3-carbonitrile CAS 80242-22-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

5-acetyl-1H-pyrrole-3-carbonitrile (CAS 80242-22-4) is a high-purity analytical reference standard with the molecular formula C7H10N2O and a molecular weight of 138.17 g/mol.

The molecular framework of 5-acetyl-1H-pyrrole-3-carbonitrile (C7H10N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H10N2O
Molecular Weight138.17 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Nitrogen Atoms2

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