3-(2-Fluorophenyl)phenol CAS 80254-63-3
| CAS No. | 80254-63-3 |
| Molecular Formula | C12H9FO |
| Molecular Weight | 188.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-(2-Fluorophenyl)phenol (CAS 80254-63-3), a certified reference material (molecular formula C12H9FO, MW 188.20 g/mol) for analytical method development and quality control.
The molecular framework of 3-(2-Fluorophenyl)phenol (C12H9FO) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9FO |
| Molecular Weight | 188.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
Related Fluorophenyl Standards
- 3-(4-Fluorophenyl)phenol (CAS 10540-41-7)
- 4-(3-Fluorophenyl)pyridin-2-amine (CAS 1159815-31-2)
- 4-(2-Fluorophenyl)pyridin-2-amine (CAS 1159817-35-2)
- 6-(4-Fluorophenyl)pyridin-2-amine (CAS 1159819-35-8)
- 6-(3-Fluorophenyl)-3-pyridinamine (CAS 1214327-17-9)
- 3-(4-Fluorophenyl)pyridin-2-amine (CAS 1214333-67-1)
- 2-(2-Fluorophenyl)pyridin-3-amine (CAS 1214351-77-5)
- 3-(4-Fluorophenyl)pyridin-4-amine (CAS 1214353-80-6)
Recommended Standards
- 3-((4-Oxo-4,5-dihydrothiazol-2-yl)amino)propanoic acid (CAS 797027-57-7)
- 3-(3-Fluorophenyl)phenol (CAS 80254-64-4)
- 2-Methoxybenzenesulfonic acid (CAS 34256-00-3)
- 5-Oxo-2-thioxo-4-imidazolidinepropanoic acid (CAS 83178-70-5)
- Diethylene glycol Mono-Methacrylate (CAS 2351-43-1)
- [(4-chlorophenyl)methyl][2-(3,4-diethoxyphenyl)ethyl]amine (CAS 1011399-13-5)
- 2-Amino-3-(1,3-dimethyl-1h-pyrazol-5-yl)propanamide (CAS 1486043-61-1)
- N-(3-amino-4-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamide hydrochloride (CAS 1193389-78-4)
- Timolol Impurity 25 (CAS CATO-C4X-149625)
- 4a-Bromoperhydroisoquinoline hydrobromide (CAS 4479-54-3)
- 2-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 1060816-56-9)
- 1-(4-bromophenyl)pentane-1,3-dione (CAS 309279-18-3)
- 4-Amino-3-methyl-N-[3-(trifluoromethyl)phenyl]benzamide (CAS 331243-98-2)
- Myelin Basic Protein (85-99) Peptide Antagonist (CAS 444305-16-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com