3-Fluoro-3′-nitro-1,1′-biphenyl CAS 80254-72-4

Purity 97%+In StockPharmaceutical Standards
CAS No.80254-72-4
Molecular FormulaC12H8FNO2
Molecular Weight217.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Fluoro-3′-nitro-1,1′-biphenyl CAS 80254-72-4 chemical structure

Description

CATO supplies 3-Fluoro-3′-nitro-1,1′-biphenyl (CAS 80254-72-4), a certified reference material (molecular formula C12H8FNO2, MW 217.20 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-Fluoro-3′-nitro-1,1′-biphenyl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 217.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H8FNO2
Molecular Weight217.20 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Halogen ContentF-containing
Nitrogen Atoms1

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