5-(Chloromethyl)isoquinoline hydrochloride CAS 80278-68-8
| CAS No. | 80278-68-8 |
| Molecular Formula | C10H8ClN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(Chloromethyl)isoquinoline hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-(Chloromethyl)isoquinoline hydrochloride (CAS 80278-68-8), molecular formula C10H8ClNHCl and molecular weight 214.09 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C10H8ClNHCl, 5-(Chloromethyl)isoquinoline hydrochloride contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 214.09 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H8ClN HCl |
| Molecular Weight | 214.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 7-(Chloromethyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-81-4)
- 7-(Chloromethyl)-2,3-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-82-5)
- 7-(Chloromethyl)-3-(4-chlorophenyl)-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-85-8)
- chloromethyl 2-ethoxy-2-methylpropanoate (CAS 1000296-74-1)
- 5-(chloromethyl)-N-(4-methylbenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-24-0)
- 5-(Chloromethyl)-7-ethoxy-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1000932-47-7)
- 5-(chloromethyl)-N-(4-fluorobenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-60-4)
- 2-(Chloromethyl)-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine (CAS 1000933-67-4)
Recommended Standards
- 3-Oxo-2-phenylprop-2-enoyl chloride (CAS 17118-70-6)
- 2-Chlorothiazolo[5,4-f]isoquinoline (CAS 35317-87-4)
- Ethyl 2-[(1,3-dioxobutyl)amino]-4-phenyl-3-thiophenecarboxylate (CAS 568559-93-3)
- N-Benzyl-3-bromo-5-nitrobenzamide (CAS 1283116-50-6)
- Tert-butyl 3-(hydroxymethyl)-2,2-dimethylazetidine-1-carboxylate (CAS 2446668-78-4)
- 5'-Amino-4-bromo-[1,1':3',1''-terphenyl]-4',6'-dicarbonitrile (CAS 119452-41-4)
- (3-(4-Bromophenyl)-1H-pyrazol-5-yl)methanol (CAS 1137165-23-1)
- N-(tert-butoxycarbonyl)-S-(4-methoxybenzyl)-D-cysteine (CAS 58290-35-0)
- 4-Bromo-6-iodo-2-methylpyrimidine (CAS 1807213-49-5)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
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