2,3,6-Trichloro-5-(trifluoromethyl)pyridine CAS 80289-91-4

Purity 97%+In StockPharmaceutical Standards
CAS No.80289-91-4
Molecular FormulaC6HCl3F3N
Molecular Weight250.43 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,3,6-Trichloro-5-(trifluoromethyl)pyridine CAS 80289-91-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,3,6-Trichloro-5-(trifluoromethyl)pyridine.

2,3,6-Trichloro-5-(trifluoromethyl)pyridine (CAS 80289-91-4), molecular formula C6HCl3F3N and molecular weight 250.43 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrile group, fluorine/chlorine substitution, an aromatic ring system, 2,3,6-Trichloro-5-(trifluoromethyl)pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 250.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,3,6-Trichloro-5-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6HCl3F3N
Molecular Weight250.43 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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