5-Bromo-N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)nicotinamide CAS 802981-45-9
| CAS No. | 802981-45-9 |
| Molecular Formula | C17H14BrN3O2S |
| Molecular Weight | 404.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 404.28 g/mol gives 5-Bromo-N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)nicotinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Bromo-N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)nicotinamide (CAS 802981-45-9), molecular formula C17H14BrN3O2S and molecular weight 404.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)nicotinamide (C17H14BrN3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Bromo-N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H14BrN3O2S |
| Molecular Weight | 404.28 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4-Bromo-N-(2-((3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl)phenyl)thiophene-2-carboxamide (CAS 1795295-70-3)
- 5-Bromo-N-(2-(p-tolyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)furan-2-carboxamide (CAS 450340-33-7)
- n-(4-Bromo-2-methylphenyl)-2-((1-phenyl-1h-tetrazol-5-yl)thio)acetamide (CAS 329779-21-7)
- N-(4-bromo-3-methylphenyl)-2-((1-phenyl-1H-tetrazol-5-yl)thio)acetamide (CAS 329078-97-9)
- 3-((5-Bromo-2,3-dihydrobenzofuran)-7-sulfonamido)thiophene-2-carboxylic acid (CAS 1268618-43-4)
- 5-(3-Bromo-5-ethoxy-4-((2-methylbenzyl)oxy)phenyl)-1,3,4-oxadiazol-2-amine (CAS 1706448-82-9)
- 5-(3-Bromo-5-ethoxy-4-((4-methylbenzyl)oxy)phenyl)-1,3,4-oxadiazol-2-amine (CAS 1706457-21-7)
- 3-Bromo-N-(6-((Cis)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methylbenzamide, 97% (CAS 1221721-86-3)
Recommended Standards
- N-(2-bromophenyl)-2-((5-(m-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetamide (CAS 332358-35-7)
- 2-{[5-(3-Bromophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]thio}acetohydrazide (CAS 324054-76-4)
- 2-{[4-(4-bromophenyl)-5-phenyl-4h-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide (CAS 893726-94-8)
- 2-((5-Benzyl-1,3,4-oxadiazol-2-yl)thio)-N-(4-bromophenyl)acetamide (CAS 220597-89-7)
- n-((3-Aminocyclobutyl)methyl)-3-methoxypropanamide (CAS 1467390-70-0)
- 2-Chloro-N,N-diethyl-4-(trifluoromethyl)thiazole-5-carboxamide (CAS 72850-84-1)
- 3-(2,4-Dimethylphenyl)-1H-pyrazole (CAS 154258-67-0)
- 2-[4-(3-methoxyphenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937606-37-6)
- 6-Bromo-2-((tert-butoxycarbonyl)amino)-3-fluorobenzoic acid (CAS 2138575-47-8)
- 2-(1H-Pyrazol-3-yl)-1H-benzo[d]imidazole (CAS 380653-63-4)
- 3-Fluoro-4-(thiophen-2-yl)aniline (CAS 1250004-13-7)
- 2-(Hept-1-en-1-yl)quinolin-4(1H)-one (CAS 60783-02-0)
- 1-(2-(2-Chloro-6H-indolo[2,3-b]quinoxalin-6-yl)acetyl)-4-(1-(4-chlorophenyl)ethylidene)-3-methyl-1H-pyrazol-5(4H)-one (CAS 119457-23-7)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
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