2-(thiophen-3-yloxy)acetic acid CAS 80305-06-2

Purity 97%+In StockPharmaceutical Standards
CAS No.80305-06-2
Molecular FormulaC6H6O3S
Molecular Weight158.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(thiophen-3-yloxy)acetic acid CAS 80305-06-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 158.18 g/mol gives 2-(thiophen-3-yloxy)acetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(thiophen-3-yloxy)acetic acid (CAS 80305-06-2) is a high-purity analytical reference standard with the molecular formula C6H6O3S and a molecular weight of 158.18 g/mol.

The molecular framework of 2-(thiophen-3-yloxy)acetic acid (C6H6O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(thiophen-3-yloxy)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H6O3S
Molecular Weight158.18 g/mol
Purity97%+
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Sulfur Atoms1

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