4-Maleimidobutyric acid N-hydroxysuccinimide ester CAS 80307-12-6
| CAS No. | 80307-12-6 |
| Molecular Formula | C12H12N2O6 |
| Molecular Weight | 280.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 280.23 g/mol gives 4-Maleimidobutyric acid N-hydroxysuccinimide ester distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Maleimidobutyric acid N-hydroxysuccinimide ester (CAS 80307-12-6), molecular formula C12H12N2O6 and molecular weight 280.23 g/mol, is a CATO reference standard with documented purity and traceability.
4-Maleimidobutyric acid N-hydroxysuccinimide ester (C12H12N2O6) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Maleimidobutyric acid N-hydroxysuccinimide ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12N2O6 |
| Molecular Weight | 280.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 2 |
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